In spite of all the advancements with carbon fiber, and even aluminum, to a lot of riders – steel is still quite real. While often a bit heavier, steel offers a comfortable ride, a stout build, and a durable frame for years of abuse. If you’re adventuring off the grid (or onto the grid of a new country), those can be very desirable traits. To satisfy the lust for CroMoly, Salsa has just unveiled their 2020 steel range with updated paint and components on the Fargo, Vaya, and Marrakesh.FargoFeaturing a new color and new Teravail Sparwood 29×2.2″ tubeless tires, the Fargo Apex 1 continues as Salsa’s steel gravel and bikepacking dropbar mountain bike.Overall, the frame looks unchanged with Cobra Kai CroMoly tubing and Alternator V1.5 dropouts which allow you to run multiple hub standards and add a single speed or belt drive set up. Tire choices include 27.5+, 29″, and even 29+. The complete Apex 1 build will go for $2,199, while the frameset includes the Firestarter 110 Deluxe fork for $999.The Fargo will also still be offered in a titanium frameset with 3/2.5 seamless tubing and a Firestarter 110 Deluxe fork for $2,799.VayaSporting a new color and a fresh Shimano GRX group, the Vaya 600 GRX is built for both on and offroad adventures. The complete bike includes Teravail Cannonball 700c x 38mm tubeless tires and a Waxwing carbon fork with additional mounts for your journey at $2,299.It is also available in a frameset with the same Waxwing fork for your own custom all-road or touring build at $999.MarrakeshAgain with a new color, the Marrakesh Sora also includes a new drivetrain with Shimano Sora shifters and a 3 x 9 drivetrain for extra range when fully loaded. Now built with the Teravail Rampart 700c x 42mm tubeless tires, the complete bike includes front and rear racks for $1,799. Or, built it up as a frameset with a Cobra Kai CroMoly frame and fork for $799.salsacycles.com
Henry Fortunato in his office at the InterUrban Art House in downtown Overland Park in May 2017.Henry Fortunato, whose love of local history and dedication to preserving it have transformed the Indian Creek Trail in Johnson County, died Monday at the age of 62.Register to continue
August 1, 2012 Regular News Santa Rosa County needs a judge Santa Rosa County needs a judge The First Circuit Judicial Nominating Commission is now accepting application to fill a Santa Rosa County court vacancy, created by the appointment of Judge Ross L. Bilbrey to the circuit bench. Applicants must be be registered voters, members of the Florida Bar for the past five years, and reside in Santa Rosa County. Applications are here. An original and 10 copies of the completed application must be received by Joseph A. Zarzaur, Jr., JNC Chair, 11 E. Romana Street, Pensacola 32502, no later than noon on August 22. For more information, contact Zarzaur at (850) 444-9299.
Share Share on Facebook When faced with a change to our environment, we have to make appropriate decisions, which usually involves the orbitofrontal cortex. Yet unexpectedly, scientists at the Institut de Neurosciences Cognitives et Intégratives d’Aquitaine (INCIA, CNRS/Université de Bordeaux) have discovered that a brain region located in the thalamus also plays a crucial role in using these evolved skills. Tested in the rat, this work is published on 23 September 2015 in The Journal of Neuroscience.All living organisms must take appropriate decisions to meet their own needs. In particular, the ability to take account of abrupt environmental changes represents a significant challenge for the survival of a species. Such decision-making is considered as an evolved cognitive function. It involves the orbitofrontal cortex, one of the most developed brain structures, known to perform decision-making processes.The “Décision et Adaptation” team at the INCIA first of all focused on the brain regions connected to the orbitofrontal cortex. Using a labeling technique, the scientists evidenced a specific area, the thalamic submedius nucleus, which is closely linked to the orbitofrontal cortex and whose functional role is unknown. Pinterest Email Share on Twitter LinkedIn The team then tested the role of these two brain structures (the submedius thalamic nucleus and orbitofrontal cortex) in decision-making and adaptive behavior. To achieve this, they studied three groups of rats: the first presented lesions to the orbitofrontal cortex, the second had lesions on the submedius nucleus and the third was made up of lesion-free control animals. The objective was to test their ability to establish a link between an auditory cue and obtaining a food reward.The experiment was organized in two phases. The initial learning phase allowed the animals to learn that two different sounds (S1 and S2) each signaled a specific food reward. The three groups of animals thus visited the food dispenser as soon as an auditory stimulus was perceived. The lesions did not prevent the animals from learning that an auditory stimulus predicts a reward. During the second phase, the procedure remained unchanged for the first cue, but for S2, the scientists distributed food rewards during, and mostly outside, cue test periods. This sound thus lost its predictive value and lesion-free animals started to take no account of the S2 auditory stimulus, only visiting the dispenser when they heard S1. On the other hand, animals with a lesion – of either the orbitofrontal cortex or the submedius thalamic nucleus – proved incapable of making this distinction, and thus of adapting.This study therefore identified the existence of a circuit between the thalamus and the cortex, which proved crucial to adaptive decision-making. The originality of this discovery lies in the key role that scientists attribute to the submedius thalamic nucleus, a structure hitherto poorly known in the field of adaptive behavior. These findings suggest that numerous functional circuits underlying this type of behavior may involve a contribution from the thalamus. The team is now planning to explore these “thalamocortical” circuits, whose understanding could shed light on numerous diseases, such as schizophrenia or addiction.
Two studies exploring potential reservoirs for MERS-CoV found evidence that the virus is widespread in camels in Nigeria but not in bats in Egypt and Lebanon.The Nigerian study, published today in Eurosurveillance, noted that RNA of MERS-CoV (Middle East respiratory syndrome coronavirus) indicated that the virus infecting camels there is distinct from strains in the Middle East, where most human cases have occurred. The virus has been previously identified in dromedary camels in the Middle East as well as in several African nations.And in the bat study, published yesterday in Emerging Infectious Diseases, researchers identified other coronaviruses in various samples from wild bats, but not MERS-CoV.About 95% of camels seropositiveFor the camel study, researchers from Hong Kong and Nigeria studied nasal swabs and blood samples collected from dromedary camels shortly after slaughter at an abattoir in Kano, Nigeria. Some of the animals originated from northern Nigeria, as well as from neighboring countries like Chad, Libya, Mali, Niger, and Sudan.The investigators collected nasal swabs from 132 camels during 7 consecutive days in January 2015 and obtained serum samples from all but 1 of those animals.Using a validated MERS-spike pseudoparticle neutralization test, the team found that 125 serum samples (95%) tested positive for antibodies to MERS-CoV. In addition, 14 (11%) of 132 nasal samples tested positive for MERS-CoV RNA by polymerase chain reaction (PCR). All 11 camels whose nasal samples tested positive were also seropositive.Phylogenetic analysis showed that the viral RNA divided into two lineages, both of which are distinct from strains analyzed in the Middle East, the authors reported.”Both of the Nigerian virus groups were distinct from previously known virus lineages,” they wrote. “The Nigerian camel viruses were most closely related to virus NRCE-HKU270 previously found in Egypt with nt sequence similarity of 99.3 to 99.6%. MERS-CoV in Nigeria were genetically distinct from viruses found in camels in the Middle East and viruses detected in humans in more recent years (nt sequence similarity ranging from 98.4 to 99.4%).”The researchers said that the findings might reflect prevalence of the virus in camels not only in Nigeria but a wider region. Not only did the camels come from other nearby countries, but they were kept within the abattoir for a number of days before slaughter, allowing for possible cross-infection and gene transfer.A study in April 2014 found a similar level of MERS-CoV–like antibodies in adult camels in Nigeria.Coronaviruses in 5% of batsIn the second study, researchers in Egypt, Lebanon, Saudi Arabia, Hong Kong, and the United States collected bat samples from February 2013 through April 2015.They captured 821 bats live in their caves and collected oral swab, rectal swab, and blood samples. All bats were released except for 72 that died or were euthanized after capture. The team took lung and liver samples from these bats. The caves were close to human-inhabited areas but not near camel herds.In Egypt, all 82 Egyptian tomb bats tested negative for CoV, while the liver of 1 of 31 desert pipistrelle bats, or 3.2%, tested positive for a betacoronavirus (beta-CoV), the family to which MERS-CoV and the SARS virus belongs.Among 257 specimens from Egyptian fruit bats, 18 (7%) tested positive for beta-CoV, while a murine hepatitis virus–like CoV was detected in the lung of 1 bat. Overall, 5.1% of the Egyptian bats tested CoV-positive.In Lebanon, all 4 Rhinolophus hipposideros and 6 Miniopterus schribersii bats tested negative for CoV, while 1 of 3 Rhinolophus ferrumequinum bats was positive. In addition, the rectal swabs of 24 (5.5%) of 438 Egyptian fruit bats from 10 different locations tested positive for beta-CoV. Overall, 5.5% of the Lebanese bats tested positive.The researchers tested a subset of 696 samples (516 from Egypt, 180 from Lebanon) for MERS-CoV using PCR, and all tested negative. And serum samples from 814 bats likewise tested negative for MERS-CoV antibodies.The authors noted, “Our detection of CoVs in oral, rectal, lung, and liver samples suggests that CoV infection in those bats was systemic, although the bats were apparently healthy.” They also said that the hepatitis virus–like infection might have originated in mice sharing the same habitat.Coronaviruses related to MERS-CoV are known to exist in bats, and a small fragment of viral material found in bat feces in Saudi Arabia in 2013 was reported to match MERS-CoV, but the finding proved controversial.See also:Dec 10 Eurosurveillance studyDec 9 Emerg Infect Dis studyApr 22, 2014, CIDRAP News story “Antibody study hints at MERS-CoV in African camels”
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GE Oil & Gas has signed a Master Service Agreement with Statoil for new subsea projects that will enable GE to continue to support the international energy company in a low oil price environment.According to GE O&G, the global agreement forms the basis for potential new contracts for subsea equipment and services on new projects and field developments. The contract is valid globally until 2025.“We are pleased to have secured an agreement with Statoil that paves the way for further and deeper collaboration between the companies within the subsea segment in the next decade,” says Tom Huuse, Managing Director of GE Oil & Gas in Norway.GE Oil & Gas recently delivered subsea production system equipment for Statoil’s Snøhvit gas field in the Barents Sea on the Norwegian Continental Shelf.In today’s oil price environment, sustained focus on costs and efficiency will ultimately be the key to develop several currently marginal prospects and discoveries, the company said.GE and Statoil are already working together in the Power Collaboration initiative, which aims to accelerate the development of sustainable cost efficient energy solutions.
Hidden Dangers – Railway Safety in the Era of Privatisationby Stanley HallPublication of this 128 page essay on safety could not have been better timed. In the wake of the hysteria that followed the Ladbroke Grove accident on October 5, this is a badly-needed sober assessment of railway safety on Britain’s railways. Those with safety responsibilities should note the forthright comments and criticisms about what should and should not happen in the aftermath of an accident. The author draws particular attention to the 65-day public enquiry into the Clapham Junction accident in December 1988 and questions the recommendations drawn up by Sir Anthony Hidden QC, who had no railway expertise. Hall is rightly concerned that accident enquiries are turning into hunts for scapegoats and are no longer seen as an attempt to find the cause so that it can be prevented from happening again. The well-illustrated book discusses the development of government regulations and notes that government cannot escape a degree of blame for many of the problems that have emerged in the last 10 years. Hall says that ’railway passengers have never been as safe as they are today’ but calls for more help to be given to drivers in obeying signals.ISBN 0711026793.ú19·99 from Midland Counties Publications, Unit 3 Maizefield, Hinckley, Leicestershire LE10 1YF, Great Britain.Tel: +44 1455 233 email@example.com
Reggae artiste Nesbeth has announced the release date for his debut album, A.M.E.N.The compilation, which is named after his late wife Ann-Marie Elliott-Nesbeth, is slated for an official release on October 26.A.M.E.N will be available for pre-order on all major digital platforms on September 28.The My Dream singer recently teased fans with the cover art for the 12-track project.
Sharing is caring! Share 10 Views no discussions Tweet Share Share NewsRegional Jamaica PM expresses sadness at US school shooting by: – December 17, 2012 Prime Minister Simpson Miller said she was still in shock and was even more saddened at the number of children who lost their lives in the senseless tragedy.KINGSTON, Jamaica, Monday December 17, 2012 – Prime Minister Portia Simpson-Miller says she is saddened by the mass killings of innocent children at the Sandy Hook Elementary School in Connecticut over the weekend, noting it is a tragedy from which their families will never recover.“I weep for the victims and especially the children, cut down in such a brutal manner and at such a tender age. On behalf of all Jamaicans, I send my deepest condolences to the families and friends who no doubt are going through a very difficult time. This is a tragedy from which they will never recover,” she said in a message.Connecticut State police spokesman Paul Vance said the gunman died at the scene and investigators had assembled “some very good evidence” to explain what drove the 20-year-old gunman to slaughter 20 children and six adults.The attacker, identified by law enforcement sources as Adam Lanza, opened fire on Friday morning at the school in Newtown, making the incident the second-deadliest US shooting, after 32 people died at Virginia Tech in 2007.Some of those killed are expected to be buried on Monday.Prime Minister Simpson-Miller said she was still in shock and was even more saddened at the number of children who lost their lives in the senseless tragedy.“I ask for God’s healing hands on those who were injured and hope that in time the persons who have lost their loved ones will find peace and be comforted.”Over the weekend, Guyana’s President Donald Ramotar described the killings as “horrific and senseless” as his country extended condolences to the United States.In a message to President Barak Obama, the Guyanese head of state said that the murders on Friday “struck a chord of grief and unbelief in the hearts of the people of Guyana”.In his condolence message President Ramotar said the thoughts and prayers of all Guyanese people were with the families of the victims “at this difficult time”.Trinidad and Tobago’s Prime Minister Kamla Persad Bissessar said the “heart-shattering” incident was a wake-up call for her country to reassess own security in schools.“It’s really a tragedy of greatest proportions. As we celebrate children and the birth of the Christ child it is really a heart-shattering thing. I can just imagine these young children so defenseless. For us here we have not had incidents such as those but our prayers are with these families there.“Whilst we sympathise our prayers go across the water to those in the US. It gives us pause for a cause to reassess our own situation,” she said, noting that the perpetrator was a 20-year-old.“Once we take care of physical security, we will also take care of emotional security. We need to engender and foster care among parents. We need to foster better education in schools and be grounded with the core values that they need to take them through the challenges they face in adult life. We have measures in place already. We will move a little faster,” she addedcaribbean360